Neurodegeneration

Platform
Large Volume Tomography
High resolution large volume tomography with electron microscopy has the potential to transform our understanding of life, by linking the atomic and molecular structure of protein complexes in their biological context – the cell.

PhD Project Area
Imaging neurodegeneration using mass spectrometry to understand the mechanisms of disease in the brain
Given the high complexity and heterogeneity of the cells in the brain, spatial information of molecular organisation is essential for the understanding of and insights into cellular processes.

Technology Innovation Challenge
Integrated Chemical Imaging in Cells and Tissues
Our aim: To drive innovations in mass spectrometry alongside other structural biology techniques to find out more about the role of molecules in biology so that we can better understand health and disease.