Protein Chemistry
Mechanistic Proteomics
Proteins are the workhorses of living cells. Proteins operate in a highly dynamic environment interacting with other proteins and other types of molecules including sugars, lipids and nucleic acids.
Fast Spectroscopy
We study how light can trigger changes in biomolecules to activate biological functions using different spectroscopic methods.
Nanobodies Discovery Platform
Nanobodies are single domain antibodies derived from the unique heavy chain only immunoglobulins of camels, llamas, and alpacas.
Native ambient mass spectrometry
Native ambient mass spectrometry (NAMS) combines spatial and structural biology by enabling untargeted label-free interrogation of proteins in their functional form directly from their physiological environment.
Chemical Biology
Cells rely on a range of biomolecules to maintain function and respond to change.
Developing biocompatible chemistries
Post-translation modifications (PTMs) are nature’s way of communicating and responding to a change in situation.
High Throughput discovery and molecular informatics
The diversity of biological, chemical and physical properties that naturally occurring proteins achieve are astounding.
Molecular Perturbations: Chemistry Engineering Biology
Our aim: To use innovative chemistries to better understand and modulate the molecules of life.