Plasma FIB/SEM

Project
Structural Neurobiology
Developing cutting edge techniques to image structures in the brain on the molecular scale so we can identify early structural changes leading to disease onset.

Project
Biochemical Microscopy for imaging across Molecular Scales
Developing a transformative cryogenic 3D biochemical microscope, harnessing the power of high-resolution electron microscopy and mass spectrometry imaging

Platform
Large Volume Tomography
High resolution large volume tomography with electron microscopy has the potential to transform our understanding of life, by linking the atomic and molecular structure of protein complexes in their biological context – the cell.

PhD Project Area
Cryogenic electron imaging for investigating the molecular sociology within cells and tissues
Electron imaging under cryogenic conditions allows cells and tissues to be imaged on multiple scales, with pristine preservation of fine molecular detail.