Microscopy
Defining how coronaviruses enter and traffic in cells
Coronaviruses are a major source of respiratory infections within the human population. Recent years have seen 3 major coronavirus outbreaks (SARS, MERS, SARS-CoV2), with several other strains causing endemic seasonal colds. A substantial zoonotic reservoir of coronaviruses exists within wild…
Structural Glycobiology
Complex carbohydrate molecules are essential for life. These diverse structures are found on every human cell and participate in a huge range of structural and signalling functions within cells, and between cells and the extracellular matrix.
Electron Detector Development
Atomic resolution imaging with electrons causes sample damage. The information per unit of damage is dependent on sample thickness and beam energy.
Stimulated Emission Depletion Microscopy (STED)
We are from investigating how cells communicate with one another, to understand more complex structures such as those found in organoid and tissue formation.
Multidimensional Imaging
Our aim: To develop new technologies to see the molecules of life and their dynamics with unprecedented detail.