Liquid phase dynamics

Project

Liquid Phase Electron Microscopy and Spectroscopy of Biological Specimens

Transient, dynamic assemblies of biomolecules in solution are the primary driving forces behind biology. However, studying these at high resolutions requires the use of electron microscopes (EM), which need extremely high vacuums to function.

Project

Chromatic Correction

Knoll, the first chromatic aberration-corrected electron microscope in the UK housed at the Franklin, will push the current resolution limits for biological samples by correcting energy variations in the electron beam.

PhD Project Area

Liquid Phase Electron Microscopy for Cellular Ultrastructure, Biochemistry and Dynamics

Fundamentally, biology is driven by transient, dynamic assemblies of biomolecules in solution.

Technology Innovation Challenge

Multidimensional Imaging of Molecular Structures

Our aim: To develop new technologies to see the molecules of life and their dynamics with unprecedented detail.