Analytical Chemistry
Fast Spectroscopy
We study how light can trigger changes in biomolecules to activate biological functions using different spectroscopic methods.
Nuclear Magnetic Resonance (NMR)
NMR spectroscopy is the only experiment that gives combined structural and dynamical information of molecules at atomic resolution, in solution. It is widely used for routine characterisation of molecules and is vital for chemical analysis.
High Throughput Discovery
The High Throughput Discovery Lab aims to accelerate the discovery of novel bioactive molecules and chemistries which enable understanding, and modulation of, biomedical mechanisms.
Dissecting the sugar-code in situ
Glycosylation – the covalent attachment of a sugar molecule to a protein – is the most abundant and indeed most complex post translational modification (PTM) in nature.
Developing biocompatible chemistries
Post-translation modifications (PTMs) are nature’s way of communicating and responding to a change in situation.
Biophysics, Spectroscopy and Spectrometry
Understanding the nature of a biomolecule requires understanding its structure and function within its native environment under a range of conditions.
Molecular Perturbations: Chemistry Engineering Biology
Our aim: To use innovative chemistries to better understand and modulate the molecules of life.
Integrated Chemical Imaging in Cells and Tissues
Our aim: To drive innovations in mass spectrometry alongside other structural biology techniques to find out more about the role of molecules in biology so that we can better understand health and disease.